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Monday, February 2, 2015


January 2015 Dr. Joseph A. Impellizeri DVM, DACVIM (Oncology)

Happy February!!
Enjoy our cold and snowy month with your pets and have a Happy Valentines Day----just keep those chocolates away from them.... :)
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Exploring the PD-L1 Pathway here at Veterinary Oncology Services
Veterinary Oncology Services is the key research center for B7-1 immunotherapy. This immune pathway follows the PD-L1 pathway showing such promise against human cancers. Go to for a great link to this research on the human side.
Cancer can evade immune destruction by upregulating the inhibitory ligand PD-L1 on tumor cells and tumor infiltrating immune cells, such as macrophages and dendritic cells. PD-L1 binds to B7-1 and PD1 on cytotoxic T cells, disabling the anticancer immune response.
For more information, please go to:

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Knicks' Carmelo Anthony invests in pet-tracking company
Mr. Anthony's Melo7 Tech Partners is among the investors in San Francisco-based Whistle, which closed a $15 million Series B financing round led by Nokia Growth Partners, the company said in a news release.
Queensbridge Venture Partners, founded by rapper Nas, whose real name is Nasir Jones, also invested, as did Qualcomm Inc. Whistle has raised a total of $25 million, the company said.
According to Whistle, the new capital will be used to develop the pet brand's product line and support the company's growth.
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New Therapies Take Hold in Fight Against Cancer
Veterinary Oncology Services is the only center involved in advanced cancer treatment with DNA cancer treatment vaccines and Electrochemotherapy (targeting the cancer and offering a significant advantage in reducing drug dosages and not harming healthy tissue). We routinely see clients from all over New York state and from as far away as Canada and Florida. Dr. Impellizeri is also a Visiting Scholar at Vassar College in Poughkeepsie, NY in the Department of Biology.
We can be reached at:

Phone: 845 205 2768

Please call us to refer a patient or visit us on our website at

We have expanded to help more animals on Long Island!!
Raw Food Diet for Pets: Trendy, But Is It Safe?

Q&A: How can I train my dogs not to bark at everything?
I have to adopted dog, one is 12 and the other is one-and-a-half. I’ve always had issues with the older one barking at everyone who walks down the street – doesn’t matter inside or out, and especially if they’re walking a dog. Now he has taught our newest family member to do this.
How can I train my dogs not to bark at everything, and only bark if someone comes to the door, and to stop once I let them know it’s okay?
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8 Tips On Attending A Dog Show Looking For A Breeder
We got a lot of great answers such as searching local and national breed clubs, searching health databases such as OFA, breed rescue groups, word of mouth, Facebook groups and attending dog events such as dog shows.
I’m a fan of all of them but I always recommend to people to try and attend a local dog show if they get a chance. A dog show can be a great way to meet responsible breeders and/or talk with other people who are familiar with the breed that you are interested in.
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